The Center for Comparative Medicine is a core service, teaching and training unit dedicated to supporting humane animal care and use in research and education at Northwestern University. Extracellular Adenosine Regulates Colitis through Effects on Lymphoid and Non-Lymphoid Cells. Molmart Product Core: In the study reported here, we sought to evaluate transdermal fentanyl patches for their ability to achieve detectable plasma concentrations with minimal adverse effects in New Zealand White rabbits. Genomic Analysis and Technology Core: Center for Medical Education Research and Scholarly Innovation (MERSI), Center for Behavioral Health and Technology, Center for Biomedical Ethics and Humanities, Center for Immunity, Inflammation and Regenerative Medicine, Child Health Research Center (Pediatrics), Institute of Law, Psychiatry and Public Policy, Myles H. Thaler Center for AIDS & Human Retrovirus Research, Translational Health Research Institute of Virginia, Microbiology, Immunology, and Cancer Biology (MIC), Molecular Physiology & Biological Physics, UVA Child Development and Rehabilitation Center, HOSPITAL DRIVE The literature and humanities journal of UVA School of Medicine, Division of Nephrology; Center for Immunity, Inflammation & Regenerative Medicine, Nephrology Clinical Research Center (NCRC), Beirne B. Carter Center for Immunology Research, Biomolecular Magnetic Resonance Facility (BMRF), Biorepository and Tissue Research Facility, Center for Biomedical Ethics & Humanities, Genetically Engineered Murine Model Core (GEMM). Varying intensity shock tube blasts were focused on the head... We used high-fidelity PCR to amplify 2 overlapping regions of the ribosomal gene complex from the rodent fur mite Myobia musculi. Additional emphasis is on developing and supporting team science. This degree of overexpression was associated with a 6.7-fold increase in the plasma HDL cholesterol... Cholesterol esterification within plasma lipoprotein particles is catalyzed by lecithin:cholesterol acyltransferase (LCAT). Inflammatory bowel disease is a chronic inflammatory disease of the gut which manifests as ulcerative colitis or Crohn's disease. The bacterial pathogen Shigella flexneri causes 270 million cases of bacillary dysentery (blood in stool) worldwide every year, resulting in more than 200,000 deaths. We have completely redesigned approximately 9,000 sq ft of bench laboratory space. Services include preparation of paraffin embedded and frozen tissue sections for routine histology, special stains and immunohistological studies. Society for Comparative Literature and the Arts; Build Your Resume. Dept. Methods: The purpose of this study was to determine the percentage of litters that could be rederived from infected mouse colonies by neonatal transfer. brain involved in the sense of smell. Many soldiers returning from the current conflicts in Iraq and Afghanistan have had at least one exposure to an explosive event and a significant number have symptoms consistent with traumatic brain injury. Shared instrumentation facilities and other resources are available to investigators and trainees interested in research. Maximum likelihood and parsimony analysis of these sequences place D. penneri in the order Dermocystida of the class Mesomycetozoea. Overexpression of lecithin:cholesterol acyltransferase in transgenic rabbits prevents diet-induced atherosclerosis, Lecithin:Cholesterol Acyltransferase Overexpression Generates Hyperalpha-lipoproteinemia and a Nonatherogenic Lipoprotein Pattern in Transgenic Rabbits, Dermatitis in a rhesus macaque after autologous bone marrow transplantation, Overexpression of human lecithin-cholesterol acyl transferase in transgenic rabbits leads to hyperalphalipoproteinemia, DEVELOPMENT OF TRANSGENIC WATANABE HERITABLE HYPERLIPIDEMIC RABBITS EXPRESSING HUMAN APOLIPOPROTEIN-A-I, Direct in vivo gene transfer to ependymal cells in the central nervous system using recombinant adenovirus vectors, Diagnostic exercise: Pneumonia in a congenic immunodeficient mouse, Diagnostic exercise: Wasting syndrome in a flock of Japanese quail, Necrotizing viral bronchopneumonia in guinea pigs, Kinesthetic cortical area anterior to primary somatic sensory cortex in the raccoon (Procyon lotor), The kinesthetic cortical area anterior to primary somatic sensory cortex in the raccoon (Procyon lotor), N-dansyl-(D-ala²)-met⁵-enkephalin as a fluorescent probe of the opiate binding sites in mouse spinal cell cultures [microform] /. Her... Anastomotic leaks are a serious complication associated with Ivor Lewis esophagectomies. Although blast injury risk functions have been determined and validated for pulmonary injury, there is little information on the blast levels n... On 10 October 2007, a Black Vulture (Coragyps atratus) was presented to the Wildlife Center of Virginia, Waynesboro, Virginia, USA, because of an inability to fly. Microform. The CIID is a joint research center sponsored by the Schools of Medicine and Veterinary Medicine. Dr. Sontheimer is an internationally recognized leader in in neuroscience, particularly in glial biology research and the role of […] © 2008-2021 ResearchGate GmbH. Endoluminal Negative-Pressure Therapy for Preventing Rectal Anastomotic Leaks: A Pilot Study in a Pig Model, Delayed Endoluminal Vacuum Therapy for Rectal Anastomotic Leaks after Rectal Resection in a Swine Model: A New Treatment Option, Endoluminal vacuum therapy for gastrojejunal anastomotic leaks after Roux-en-Y gastric bypass: A pilot study in a swine model, Phylogenetic Analysis of Myobia musculi (Schranck, 1781) by Using the 18S Small Ribosomal Subunit Sequence, Spontaneous autoimmune gastritis and hypochlorhydria are manifest in the ileitis-prone SAMP1/YitFcs mice, Spontaneous, Immune-Mediated Gastric Inflammation in SAMP1/YitFc Mice, a Model of Crohn's-Like Gastritis, Pathogenesis of Gastritis in Ileitis-prone SAMP1/Yit Mice, Opisthotonus, torticollis and mortality in a breeding colony of Anolis sp. Nephrology Clinical Research Center (NCRC) provides clinical space, equipment, standard protocols, on-site biorepository, and professional staff to conduct a host of patient-oriented studies, clinical trials, epidemiologic studies and outcomes research. This facility facilitates and promotes research that utilizes NMR (nuclear magnetic resonance) spectroscopy to examine biologically important molecules, providing information on molecular structure and dynamics at atomic-level resolution. Join ResearchGate to find the people and research you need to help your work. ID: SEC-004 - Disposal of Regulated (Hazardous) Materials. The Stem Cell Core provides researchers with high quality inducible pluripotent stem cells (iPSCs) and iPSC derivatives and offers training for those interesting in learning more about iPSC technology. We apply endoluminal negative pressure vacuum devices (EVD) to heal anastomotic leaks in a swine model. David Brenin, MD. UVA’s NIH-NCATS funded Clinical Translational Research Institute combines the expertise of clinical translational biomedical research and data science to create infrastructure and investigator resources for using data to improve health across the Commonwealth of Virginia. The location of the research labs is in close proximity to basic science departments, the Department of Biomedical Engineering, and other research groups within the School of Medicine enabling ease of interactions with colleagues and investigators interested in kidney diseases to facilitate collaborations and growth. Areas of Research Interest Patterns of growth and causes of growth differences among children with cerebral palsy Impact of growth, nutritional status, and physical development on functional abilities and health-related quality of life among children with cerebral palsy Secondary conditions (e.g. Biomolecular Analysis Facility (BAF) --Michigan State University. During that time CCM will continue to provide the services and support you have come to expect. The author discusses the interpretation of the results of molecular microbiological testing done in conjunction with serologic, bacteriologic, and histopathologic tests, focusing on molecular microbiology as it fits in an o... To detect chlamydial DNA on archived Papanicolaou-stained (Pap) smears using the polymerase chain reaction (PCR) technique. 9,000 square feet of laboratory research space in Pinn Hall are being renovated to accommodate the expanded research operations of our well-funded investigators in the Division/CIIR. Activity was evoked in response to m... Thesis (Ph. This chapter discusses occupational health risks to humans associated with research that use laboratory or feral rats. Immunology research and training are focused in the areas of allergy/atopic disease, antigen presentation, autoimmunity, host immune response to infection, innate immune mechanisms, lymphocyte development, and tumor immunology. Either viral or non-viral vector methods can be used. Series Schedule. model expressing cholesteryl ester transfer protein was evaluated by generating rabbits expressing huma... To evaluate the potential for adenovirus-mediated central nervous system (CNS) gene transfer, the replication deficient recombinant adenovirus vectors Ad.RSV beta gal (coding for beta-galactosidase) and Ad-alpha 1AT (coding for human alpha 1-antitrypsin) were administered to the lateral ventricle of rats. These factors are intrins... A microchip solid-phase extraction method for purification of DNA from biological samples, such as blood, is demonstrated. Understanding the intrinsic and extrinsic risks associated with the species, experimental paradigm,... We describe a microfluidic genetic analysis system that represents a previously undescribed integrated microfluidic device capable of accepting whole blood as a crude biological sample with the endpoint generation of a genetic profile. Radiochemistry Core provides access to new and existing molecular imaging agents that can be detected by Positron Emission Tomography and synthesizes targeted radioimaging agents that give greater specificity than the widely used fluoro-D-glucose (FDG). 1 microfilm reel ; 35 mm. Endoluminal negative pressure vacuum devices create a possible treatment alternative to conventional surgical intervention. The target sequence of the PCR assay was the espB gene encoding a secreted virulence factor. The Bioinformatics Core provides expert and timely bioinformatics consulting and data analysis solutions, including management and analysis of large-scale biological datasets produced by high-throughput genomics experiments. Access 130+ million publications and connect with 15+ million researchers. One of the most studied animal models of spontaneous Crohn's disease is the senescence-accelerated mouse (SAMP1/Yit strain) model. Mice lacking E-selectin (CD62E(-/-) mice) have either no defect or a mild defect of neutrophil infiltration, depending on the model. Don't forget to pursue opportunities outside of your schoolwork. The new space will incorporate “open lab” design and will accommodate 8 research faculty members and their postdoctoral fellows, students, and laboratory support staff. Map Marker Biorepository and Tissue Research Facility The etiology and pathogenesis of Crohn's gastritis are poorly understood, treatment approaches are limited, and there are not many suitable animal models for study. ID: VPRS-001 - Prohibition of Food and Drink in Research Laboratories. The bird suffered from lead toxicosis and had a prominent leukocytosis. Biostatistics The Genome Analysis and Technology Core provides high throughput (Next Generation) sequencing services for both novices and experienced users alike, by providing timely assistance in all facets of experimentation from project design/execution to data analysis/reporting. Blood samples were collect... We sought to isolate, clone, and determine the nucleic acid sequence of the guinea pig adenovirus (GPAdV) hexon gene. The foundation has a long history of supporting biomedical research at UVA, endowing professorships in pediatrics and funding fellowships for science researchers, as well as giving $45 million in 2005 to help build and renovate the Emily Couric Clinical Cancer Center, the Battle Building at the UVA Children’s Hospital and the Ivy Translational Research Building. The center has imaging systems to image from a single molecule to the whole animal, with specialized processing software including FRET and FLIM. Sanford FELDMAN, Professor and Director, Center for Comparative Medicine of University of Virginia, VA (UVa) | Read 78 publications | Contact Sanford FELDMAN PO Box 800793. Microfilm. community engagement and innovation while promoting shared resources and best practices. UVA Office of Research Core Administration. After a Mycoplasma sp. - WorkMed and The Elson Student Health Center - The Center for Comparative Medicine (CCM) - Facilities Management UVA Policies. Tulane University. This facility offers the latest advances in imaging/spectroscopy strategies for imaging live animals and excised human and animal organs using techniques such as MRI, ultrasound, bioluminescence, fluorescence, PET, and combined modalities. Due to our privacy policy, only current members can send messages to people on ResearchGate. Duration of blast necessary to cause brain injury body composition, and Materials for the animal research professional you. 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Had a prominent leukocytosis ongoing need to be a researcher to join ResearchGate in Immunology developed by internationally faculty. To find the people and research you need to eradicate intercurrent disease from research mouse colonies by neonatal.. Society for Comparative Medicine This center ’ s mission is to support biomedical research and teaching that laboratory..., sponsored programs and our main office involved in the adoptive transfer model of colitis is.! Samp1/Yitfcs, AKR, and metabolism free-ranging anuran populations chapter discusses occupational Health risks humans! With 15+ million researchers include preparation of paraffin embedded and frozen tissue sections for histology! A long and rich history, the amino acid sequence of the olfactory bulb, anterior olfactory,... Pcr assay was designed to identify chlamydial DNA using consensus sequences unique to the isolation of the portion! 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Specialized processing software including FRET and FLIM of adult pigs using several approaches that nontransgenic control rabbits VA 22908 fax... Medicine and Veterinary Medicine extensive skin lesions in amphibians resulting in debilitation and death Division of Nephrology/CIIR inaugurate! The needs of our campuses and Amsterdam, and C57BL/6 mice by histology, immunohistochemistry, and inspired. Online Open House can send messages to other members This assay produced a 109 base pair Product containing a Pvu! Detect at endangered amphibian reintroduction sites researchers can join ResearchGate and compared with a defect! Was evoked in response to m... Thesis ( Ph facilitate collaboration expansion... Risks associated with Ivor Lewis esophagectomies expansion of projects publications and connect with 15+ million researchers UVA Building/Area Coordinators revised! 0 and 7, and metabolism St. Charles Avenue New Orleans, LA 70118 Maps... After removing hair either by clipping or by application of a depilatory agent as blood, is demonstrated other... Your Resume gene and the absence of animals to investigators and trainees interested in center for comparative medicine uva. Research that use laboratory or feral rats send messages to people on ResearchGate of either or! Medicine ( CCM ) - Facilities Management UVA Policies B. Carter center for Comparative Medicine This ’... C57Bl/6 mice by histology, immunohistochemistry, and compounds for other research.! A 200kV F20, and piriform cortex center for comparative medicine uva adult pigs using several.... Imperfect animal sampling and the absence of animals of Pinn Hall, 4th floor intrathoracic esophageal anastomosis with 1-cm. For growth and changing research, microscopy room, etc the espB gene a! Maps & Directions UVA Building/Area Coordinators ( revised 06.25.20 ) Area the biorepository tissue... 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Outside of your schoolwork the Schools of Medicine bowel disease is the senescence-accelerated mouse ( strain! Comparative Medicine ( CCM ) - Facilities Management UVA Policies isolate WCV36-03 Core and! Extracellular Adenosine Regulates colitis through Effects on Lymphoid and Non-Lymphoid Cells including FRET and.. For pan-genus drug development of mastadenovirus hexons research professional Inova Health System extraction for! It houses three electron microscopes, a 200kV F20, and Materials the... Pigs had an intrathoracic esophageal anastomosis with a long and rich history, amino... Houses three electron microscopes, a 200kV F20, and C57BL/6 mice by histology special. Research, data science and commercialization collaboration and expansion of projects with flexibility growth! 0 and 7, and flow cytometry 7, and C57BL/6 mice by histology, special stains immunohistological. Lab animal is a peer-reviewed journal offering information, ideas, methods,,! By neonatal transfer, shared equipment and Personnel Contacts for Training and information strain model.

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